供biovendor MxA Protein Human ELISA 欣博盛供
货号:RD194349200R
名称:MxA Protein Human ELISA
规格:96 wells (1 kit)
产品描述:
人MXA蛋白(粘液virus抗性蛋白1)是MX1基因的产物,是由662个氨基酸残基组成的76kDa蛋白,属于大GTPase的动态超家族。MXA蛋白在细胞对抗各种virus(包括流感、副流感、麻疹、柯萨奇、乙型肝炎virus和thogotovirus)的抗virus活性中起着重要作用。virus在其生命周期的早期、宿主细胞进入后不久和基因组扩增前被MXA蛋白抑制。小鼠mxa(mx1-gtpase)聚集在细胞核内,与核体结合,抑制已知在细胞核内复制的流感virus和thogotovirus。人MXA蛋白也聚集在细胞质和内质网中。内质网的膜室似乎提供了一个促进virus目标识别的相互作用平台。MXA似乎通过感知和捕获核衣壳样结构来检测virusinfect。因此,virus成分无法用于产生新的virus颗粒。virusMXA蛋白的表达仅由干扰素α和干扰素β以剂量依赖性方式诱导,而不是由干扰素γ、IL-1、TNFα或其他细胞因子诱导。在临床诊断中,MXA蛋白作为virusinfect的标志物可能比其他诱导蛋白(如2',5’-寡腺苷酸合成酶)更具优势,因为其基础浓度非常低,半衰期较长。一些临床研究报告了MXA蛋白在外周血单个核细胞中的表达可能作为区分virus性和细菌性疾病的标志物,以及在慢性virus性肝炎和多发性硬化的干扰素treatment过程中I型干扰素生物可利用性的可靠标志物。
特点:
It is intended for research use only.
The total assay time is less than 3 hours.
The kit measures MxA protein in whole blood (cell lysate).
Assay format is 96 wells.
Standard is native MxA protein based.
Components of the kit are provided ready to use, concentrated or lyophilized
类型:Sandwich ELISA, Biotin-labelled antibody
别名:Myxovirus resistance protein 1
物种:Human
校准范围:0.375–12 ng/ml
检测限:0.001 ng/ml
回收率:99,70%
稀释线性:95,60%
应用:Whole blood
运输:At ambient temperature. Upon receipt, store the product at the temperature recommended below.
储存/到期:Store the complete kit at 2–8°C. Under these conditions, the kit is stable until the expiration date (see label on the box).
试剂盒组成:
Antibody Coated Microtiter Strips 96 wells
Biotin Labelled Antibody 1.3 ml
Streptavidin-HRP Conjugate 13 ml
Master Standard 2 vials
Dilution Buffer 2 x 15 ml
Wash Solution Conc.(10x) 100 ml
Substrate Solution 13 ml
Stop Solution 13 ml
Product Data Sheet + Certificate of Analysis 1 pc
Biovendor是欧洲的一家生物医药科技公司,其科研及诊断产品事业部成立于1995年。Biovendor公司专注于研发与生产诊断及科研用途的免疫检测试剂盒、抗体以及重组蛋白等产品。
产品覆盖以下研究领域, 主要提供ELISA试剂盒,重组蛋白及相关抗体
凋亡(Apoptosis) |
糖尿病-胰岛素、C-肽、胰岛素原 (Diabetology - Insulin, C-Peptide, Proinsulin) |
肌生长调控 (Muscle Growth Control) |
自身免疫 (Autoimmunity) |
糖尿病-其他相关产品 (Diabetology - Other Relevant Products) |
神经组织标志物 (Neural Tissue Markers) |
血压调节和NO代谢 (Blood Pressure Regulation And NO Metabolism) |
能量代谢和体重调节 (Energy Metabolism And Body Weight Regulation) |
肿瘤学 (Oncology) |
骨与软骨代谢 (Bone And Cartilage Metabolism) |
生长hormone和生长因子相关 (Growth Hormone And Factor-related Products) |
氧化应激 (Oxidative Stress) |
心血管疾病 (Cardiovascular Disease) |
免疫应答、infect和炎症反应 (Immune Response, Infection And Inflammation) |
胰调控分子 (Pancreatic Regulatory Molecules) |
细胞粘连蛋白 (Cell Adhesion Proteins) |
免疫学 (Immunology) |
肾脏疾病 (Renal Disease) |
细胞因子、趋化因子及相关分子 (Cytokines And Chemokines And Related Molecules) |
铁代谢(Iron Metabolism) |
生殖 (Reproduction) |
糖尿病-自身免疫 (Diabetology – Autoimmunity) |
脂蛋白代谢 (Lipoprotein Metabolism) |
细胞表面蛋白 (Cell Surface Proteins (sCD) ) |
分泌型磷脂酶A2 (Secreted Phospholipases A2 show all) |
血清学 (Serology) |
类固醇hormone (Steroid Hormones) |
移植 (Transplantation) |
动物相关研究 (Animal Studies) |
其他研究领域 (Others) |
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